repeat sequences in synthetic yeast

[stormsewer]

So, they replaced 1% of the yeast genome with synthetic sequence. (The actual paper is available via paywall here (or via DOI).) The funny thing to me is that they removed repeat sequences from the original, saying they were destabilizing, and then added in a bunch more repeat sequences themselves. I suppose the synthetic repeats are much shorter than the natural repeats, and thus perhaps less likely to cause problems, but it still seems ironic.